The criteria for chain replacement is more to do with chain wear rather than chain age. The chain on my 1260 Multistrada Enduro has done 19,000 miles and still has a good few thousand left in it. I put this down to fitting a Scottoiler from new. You’ll know when the chain needs replacing when you have to start adjusting it more frequently.
You need a test ride on an Enduro to decide having ridden the 1260s. I tried both, albeit a couple of years before buying a 1260s and at the time (2016) it was the earlier model 1200 DVTs. I preferred the road focus of the s. The Enduro gave me the feeling of a lot of bulk up ahead of me which I didn't like.
Photo by Spenser Robert. For 2021, the Multistrada gets another overhaul, most notably with the application of radar technology and Ducati’s flagship, V-four engine. But, this is more than just a V4 Stradale transplant from the Panigale or Streetfighter. The counter-rotating crankshaft design remains in the Multi’s new V4 Grantourismo
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ducati multistrada 1260 enduro review